Acne fulminans (AF) is a severe form of inflammatory and ulcerated acne associated with fever, malaise, joint swellings and polyarthralgia.1 Osteoarticular lesions are often described and can be radiologically indistinguishable from those observed in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome.2,3 SAPHO is an autoinflammatory disease characterized by osteoarticular and cutaneous manifestations, the latter including nodular and fulminans acne, hidradenitis suppurativa and palmoplantar pustulosis.3 Thus, AF is considered part of the SAPHO spectrum.1
Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra / Oranges, Teresa; Insalaco, Antonella; Diociaiuti, A; Carnevale, C; Strippoli, Raffaele; Zambruno, G.; Toma, P.; El Hachem, Maya. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 0926-9959. - 31:6(2017). [10.1111/jdv.14022]
Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra.
Raffaele Strippoli;
2017
Abstract
Acne fulminans (AF) is a severe form of inflammatory and ulcerated acne associated with fever, malaise, joint swellings and polyarthralgia.1 Osteoarticular lesions are often described and can be radiologically indistinguishable from those observed in synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome.2,3 SAPHO is an autoinflammatory disease characterized by osteoarticular and cutaneous manifestations, the latter including nodular and fulminans acne, hidradenitis suppurativa and palmoplantar pustulosis.3 Thus, AF is considered part of the SAPHO spectrum.1| File | Dimensione | Formato | |
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